[Metabolism] has been a major component of teaching biochemistry to medical and life-science students, and has typically been taught as if the whole complicated organization was arbitrary or haphazard, the result of a whole series of accidents […] over the long period of evolution since the origin of life some thousands of millions of years ago. I shall try to convince you that this view is wrong […].

Cornish-Bowden A (2004) The Pursuit of Perfection: Aspects of Biochemical Evolution Oxford University Press